Steviol hydrate

• Catalog No.: H8664
• CAS Number: 471-80-7(anhydrous)
• M. F.: C20H32O4
• M. W.: 336.46568
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: Steviol
• IUPAC name: (1R,4S,5R,9S,10R,13S)-13-hydroxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^1,^1^0.0^4,^9]hexadecane-5-carboxylic acid hydrate
• IUPAC Traditional name: steviol hydrate
• Synonyms: (4α)-13-hydroxykaur-16-en-18-oic acid; (4α)-13-Hydroxykaur-16-en-18-oic acid hydrate

DATABASE IDS

• CAS Number: 471-80-7(anhydrous)
• MDL Number: MFCD20441965

PROPERTIES

• Empirical Formula (Hill Notation): C20H30O3 · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO: >10 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

Description (简体中文)

Biochem/physiol Actions
Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.