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Dynasore hydrate

Catalog No. D7693 Name Sigma Aldrich
CAS Number 1202867-00-2 Website http://www.sigmaaldrich.com
M. F. C18H16N2O5 Telephone 1-800-521-8956
M. W. 340.33004 Fax
Purity Email
Storage protect from light Chembase ID: 154075

SYNONYMS

Title
Dynasore 一水合物
IUPAC name
N'-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide hydrate
IUPAC Traditional name
N'-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide hydrate
Synonyms
3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide hydrate
3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide 一水合物

DATABASE IDS

MDL Number MFCD11045288
CAS Number 1202867-00-2

PROPERTIES

Empirical Formula (Hill Notation) C18H14N2O4 · xH2O
Apperance off-white powder
Solubility DMSO: ≥10 mg/mL
Solubility H2O: insoluble
GHS Pictograms GHS09
GHS Signal Word Warning
GHS Hazard statements H400
European Hazard Symbols Nature polluting Nature polluting (N)
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves
GHS Precautionary statements P273
RID/ADR UN 3077 9/PG 3
Risk Statements 50
Safety Statements 22-24/25-61
Storage Condition protect from light
Storage Temperature -20°C
Hazard Class 9
UN Number 3077
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Dynasore is a cell-permeable, reversible noncompetitive dynamin 1 and dynamin 2 GTPase activity inhibitor.
General description
Dynasore is a small molecule GTPase inhibitor that targets dynamin-1, dynamin-2 and Drp1 (mitochondrial). Dynasore blocks dynamin-dependent endocytosis, scission of endocytic vesicles. Dynosore is profibrotic, induces PAI-1 in pleural mesothelial cells, and may be an effective pleurodesing (pleurodesis) agent. Dynasor blocks human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.
Description (简体中文)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Dynasore is a cell-permeable, reversible noncompetitive dynamin 1 and dynamin 2 GTPase activity inhibitor.
General description
Dynasore is a small molecule GTPase inhibitor that targets dynamin-1, dynamin-2 and Drp1 (mitochondrial). Dynasore blocks dynamin-dependent endocytosis, scission of endocytic vesicles. Dynosore is profibrotic, induces PAI-1 in pleural mesothelial cells, and may be an effective pleurodesing (pleurodesis) agent. Dynasor blocks human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.

REFERENCES