SANT-1

• Catalog No.: S4572
• CAS Number: 304909-07-7
• M. F.: C23H27N5
• M. W.: 373.49398
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-benzyl-N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylidene]piperazin-1-amine
• IUPAC Traditional name: 4-benzyl-N-[(3,5-dimethyl-1-phenylpyrazol-4-yl)methylidene]piperazin-1-amine
• Synonyms: (4-Benzyl-piperazin-1-yl)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethylene)-amine

DATABASE IDS

• MDL Number: MFCD01827306
• CAS Number: 304909-07-7

PROPERTIES

• Empirical Formula (Hill Notation): C23H27N5
• Purity: ≥98% (HPLC)
• Apperance: powder
• Solubility: DMSO: >10 mg/mL
• Solubility: H2O: <2 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
SANT-1 is a potent sonic hedgehog pathway (Shh) antagonist that directly inhibits by binding to the smoothened (Smo) receptor. SANT-1 inhibits wild type and oncogenic Smo with equal potency.

Description (简体中文)

Biochem/physiol Actions
SANT-1 is a potent sonic hedgehog pathway (Shh) antagonist that directly inhibits by binding to the smoothened (Smo) receptor. SANT-1 inhibits wild type and oncogenic Smo with equal potency.