MBP (85-99) peptide antagonist trifluoroacetate salt

• Catalog No.: M0571
• CAS Number: 444305-16-2(freebase)
• M. F.: C72H115F3N18O23
• M. W.: 1657.7855096
• Purity: 95% (HPLC)

SYNONYMS

• Title: MBP (85-99) peptide antagonist
• IUPAC name: (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}ethyl]carbamoyl}-4-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-2-amino-4-carboxybutanamido]hexanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-methylbutanamido]butanoic acid; trifluoroacetic acid
• IUPAC Traditional name: (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}ethyl]carbamoyl}-4-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-2-amino-4-carboxybutanamido]hexanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-methylbutanamido]butanoic acid; trifluoroacetic acid

DATABASE IDS

• CAS Number: 444305-16-2(freebase)

PROPERTIES

• Compostion: Peptide content, 63% HPLC
• Empirical Formula (Hill Notation): C70H114N18O21 · xC2HF3O2
• Purity: 95% (HPLC)
• Shipped in: dry ice
• Apperance: lyophilized powder
• Solubility: H2O: >1 mg/mL
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala- Ala- Ala- Ala-Pro-Ala
Biochem/physiol Actions
MBP (85-99) peptide antagonist inhibits the binding of MBP 85-99 to HLA-DR2 and IL-2 and is a tool for MS research. The peptide antagonist is a 15-mer peptide that competes with Myelin Basic Protein MBP (85-99), the immunodominant epitope of MBP and major candidate autoantigen in multiple sclerosis (MS).

Description (简体中文)

Amino Acid Sequence
Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala- Ala- Ala- Ala-Pro-Ala
Biochem/physiol Actions
MBP (85-99) peptide antagonist inhibits the binding of MBP 85-99 to HLA-DR2 and IL-2 and is a tool for MS research. The peptide antagonist is a 15-mer peptide that competes with Myelin Basic Protein MBP (85-99), the immunodominant epitope of MBP and major candidate autoantigen in multiple sclerosis (MS).