Phenyl β-D-thioglucopyranoside

• Catalog No.: 04846
• CAS Number: 2936-70-1
• M. F.: C12H16O5S
• M. W.: 272.31744
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(phenylsulfanyl)oxane-3,4,5-triol
• IUPAC Traditional name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(phenylsulfanyl)oxane-3,4,5-triol
• Synonyms: Phenyl β-D-thioglucoside; Phenyl 1-thio-β-D-glucopyranoside

DATABASE IDS

• CAS Number: 2936-70-1
• MDL Number: MFCD00064097

PROPERTIES

• Empirical Formula (Hill Notation): C12H16O5S
• Impurities: 11.1-12.4% sulfur content
• Purity: ≥98% (HPLC)
• Optical Rotation: [α]/D +48.5±2.0°, c = 1 in ethanol
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Inhibition studies of a broad-specificity β-D-glucosidase2
Biochem/physiol Actions
Phenyl β-D-thioglucopyranoside was shown to inhibit the activity of sodium-D-glucose cotransporter (SGLT) 1 and 2 by a competitive inhibition mechanism. Phenyl β-D-thioglucopyranoside had a stronger inhibitory effect on SGLT2 than 1. 1

Description (简体中文)

Application
Inhibition studies of a broad-specificity β-D-glucosidase2
Biochem/physiol Actions
Phenyl β-D-thioglucopyranoside was shown to inhibit the activity of sodium-D-glucose cotransporter (SGLT) 1 and 2 by a competitive inhibition mechanism. Phenyl β-D-thioglucopyranoside had a stronger inhibitory effect on SGLT2 than 1. 1