1(S),9(R)-(-)-Bicuculline methchloride

• Catalog No.: B7686
• CAS Number: 38641-83-7
• M. F.: C21H20ClNO6
• M. W.: 417.8396
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: (5S)-6,6-dimethyl-5-[(10R)-12-oxo-3,5,11-trioxatricyclo[7.3.0.0^2,^6]dodeca-1,6,8-trien-10-yl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride
• IUPAC Traditional name: (5S)-6,6-dimethyl-5-[(10R)-12-oxo-3,5,11-trioxatricyclo[7.3.0.0^2,^6]dodeca-1,6,8-trien-10-yl]-2H,5H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride

DATABASE IDS

• MDL Number: MFCD00055233
• CAS Number: 38641-83-7

PROPERTIES

• Linear Formula: C21H20NO6Cl
• Purity: ≥97% (HPLC)
• Apperance: powder
• Solubility: H2O: >10 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RID/ADR: UN 1544 6.1/PG 3
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
1(S),9(R)-(-)-Bicuculline methchloride is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels.

Description (简体中文)

Biochem/physiol Actions
1(S),9(R)-(-)-Bicuculline methchloride is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels.