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3-Benzidino-6-(4-chlorophenyl)pyridazine_Molecular_structure_CAS_901773-91-9)
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3-Benzidino-6-(4-chlorophenyl)pyridazine

Catalog No. B6936 Name Sigma Aldrich
CAS Number 901773-91-9 Website http://www.sigmaaldrich.com
M. F. C22H17ClN4 Telephone 1-800-521-8956
M. W. 372.85018 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154052

SYNONYMS

IUPAC name
N-[4-(4-aminophenyl)phenyl]-6-(4-chlorophenyl)pyridazin-3-amine
IUPAC Traditional name
N-[4-(4-aminophenyl)phenyl]-6-(4-chlorophenyl)pyridazin-3-amine
Synonyms
BCP

DATABASE IDS

MDL Number MFCD11046030
CAS Number 901773-91-9

PROPERTIES

Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P301 + P310
RID/ADR UN 2811 6.1/PG 3
Risk Statements 22
Storage Temperature 2-8°C
Empirical Formula (Hill Notation) C22H17N4Cl
Purity ≥98% (HPLC)
Apperance light yellow solid
Solubility DMSO: >14 mg/mL

DETAILS

Description (English)
Biochem/physiol Actions
3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.
Description (简体中文)
Biochem/physiol Actions
3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

REFERENCES