α-Hydroxyisobutyronitrile β-D-glucopyranoside

• Catalog No.: 68264
• CAS Number: 554-35-8
• M. F.: C10H17NO6
• M. W.: 247.24508
• Purity: ≥98.0% (HPLC)

SYNONYMS

• IUPAC name: 2-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanenitrile
• IUPAC Traditional name: linamarin
• Synonyms: Linamarin; 2-(β-D-Glucopyranosyloxy)-2-methylpropionitrile; α-Hydroxyisobutyronitrile β-D-glucose

DATABASE IDS

• MDL Number: MFCD00036209
• CAS Number: 554-35-8

PROPERTIES

• Empirical Formula (Hill Notation): C10H17NO6
• Purity: ≥98.0% (HPLC)
• Optical Rotation: [α]/D -25.5±1.5°, c = 1 in H2O
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H332-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 20/22-36/37/38
• RTECS: TZ4850000
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Linamarin is a cyanogenic glucoside found in the leaves and roots of plants such as cassava, lima beans, and flax. Upon exposure to enzymes and gut flora in the human intestine, linamarin and its methylated relative lotaustralin can decompose to the toxic chemical hydrogen cyanide
Application
Linamarin, a cyanogenic glucose substrate, is used together with β-glucosidase, linamarase, to produce cyanide in vivo as a potential anticancer strategy.

Description (简体中文)

Biochem/physiol Actions
Linamarin is a cyanogenic glucoside found in the leaves and roots of plants such as cassava, lima beans, and flax. Upon exposure to enzymes and gut flora in the human intestine, linamarin and its methylated relative lotaustralin can decompose to the toxic chemical hydrogen cyanide
Application
Linamarin, a cyanogenic glucose substrate, is used together with β-glucosidase, linamarase, to produce cyanide in vivo as a potential anticancer strategy.