SB-505124 hydrochloride hydrate

• Catalog No.: S4696
• CAS Number: 694433-59-5(freebase)
• M. F.: C20H24ClN3O3
• M. W.: 389.87586
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: 2-[4-(2H-1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine hydrate hydrochloride
• IUPAC Traditional name: 2-[5-(2H-1,3-benzodioxol-5-yl)-2-tert-butyl-3H-imidazol-4-yl]-6-methylpyridine hydrate hydrochloride
• Synonyms: 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride hydrate

DATABASE IDS

• MDL Number: MFCD11045901
• CAS Number: 694433-59-5(freebase)
• PubChem SID: 24724611

PROPERTIES

• Empirical Formula (Hill Notation): C20H21N3O2 · xHCl · yH2O
• Purity: ≥98% (HPLC)
• Apperance: yellow powder
• Solubility: DMSO: >10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Condition: desiccated
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
SB-505124 is an inhibitor of activin receptor-like kinase (ALK) 5, also known as transforming growth factor-α type I receptor kinase, with an IC50 of 47 ± 5 nM.

Description (简体中文)

Biochem/physiol Actions
SB-505124 is an inhibitor of activin receptor-like kinase (ALK) 5, also known as transforming growth factor-α type I receptor kinase, with an IC50 of 47 ± 5 nM.