CHM-1 hydrate

• Catalog No.: C1244
• CAS Number: 154554-41-3(anhydrous)
• M. F.: C16H12FNO4
• M. W.: 301.2691832
• Purity: ≥99% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: 6-(2-fluorophenyl)-2H,5H,8H-[1,3]dioxolo[4,5-g]quinolin-8-one hydrate
• IUPAC Traditional name: 6-(2-fluorophenyl)-2H,5H-[1,3]dioxolo[4,5-g]quinolin-8-one hydrate
• Synonyms: NSC 656158; 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate

DATABASE IDS

• CAS Number: 154554-41-3(anhydrous)
• MDL Number: MFCD11114577

PROPERTIES

• Empirical Formula (Hill Notation): C16H10FNO3 · xH2O
• Purity: ≥99% (HPLC)
• Apperance: solid
• Solubility: DMSO: ≥5 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Condition: desiccated
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
CHM-1 possess antimitotic antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization.

Description (简体中文)

Biochem/physiol Actions
CHM-1 possess antimitotic antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization.