Cytochalasin B from Drechslera dematioidea

• Catalog No.: C2743
• CAS Number: 14930-96-2
• M. F.: C29H37NO5
• M. W.: 479.60778

SYNONYMS

• Title: 细胞松弛素 B 来源于Drechslera dematioidea
• IUPAC name: (5R,9R,13S,15S,15aS,16S,18aS,18bS)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,13H,14H,15H,15aH,16H,17H,18H,18bH-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
• IUPAC Traditional name: cytochalasin B
• Synonyms: Phomin

DATABASE IDS

• Beilstein Number: 1096207
• MDL Number: MFCD00077704
• CAS Number: 14930-96-2

PROPERTIES

• Concentration: 10 mg/mL in DMSO
• Empirical Formula (Hill Notation): C29H37NO5
• Shipped in: wet ice
• Sterility: 0.2 μm filtered
• Flash Point: 85 °C
• Flash Point: 185 °F
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H330
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P260-P284-P310
• RID/ADR: UN 3140 6.1/PG 3
• Risk Statements: 23/24/25
• Safety Statements: 36/37-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 3140
• Packing Group: 3
• German water hazard class: 2

DETAILS

Description (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Cytochalasin B is used to inhibit sugar transport in fibroblasts 1, decrease cytoskeletal actin and myosin in rabbit neutrophils 2, and to stimulate B lymphocytes 3.
Biochem/physiol Actions
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,4 and in studies on cytokinesis.5 Probe for the two hexose-transport systems in rat L6 myoblasts.6
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Cytochalasin B is used to inhibit sugar transport in fibroblasts 1, decrease cytoskeletal actin and myosin in rabbit neutrophils 2, and to stimulate B lymphocytes 3.
Biochem/physiol Actions
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,4 and in studies on cytokinesis.5 Probe for the two hexose-transport systems in rat L6 myoblasts.6
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.