ARP 101

• Catalog No.: A8356
• CAS Number: 849773-64-4
• M. F.: C20H26N2O5S
• M. W.: 406.49584
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: APR 101
• IUPAC name: (2R)-N-hydroxy-3-methyl-2-[N-(propan-2-yloxy)4-phenylbenzenesulfonamido]butanamide
• IUPAC Traditional name: (2R)-N-hydroxy-2-(N-isopropoxy4-phenylbenzenesulfonamido)-3-methylbutanamide
• Synonyms: (R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide; (2R)-2-[([1,1′-Biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-butanamide

DATABASE IDS

• CAS Number: 849773-64-4
• MDL Number: MFCD09753277

PROPERTIES

• Empirical Formula (Hill Notation): C20H26N2O5S
• Purity: ≥98% (HPLC)
• Apperance: solid
• Solubility: DMSO: >20 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
ARP 101 is a MMP-2 selective inhibitor. ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development, and embryogenesis.
Biochem/physiol Actions
ARP 101 is a MMP-2 selective inhibitor (Gelatinase A, EC 3.4.24.24; TBE-1; LG4A; MONA; Type IV Collagenase). ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development and embryogenesis. IC50 = 0.81 nM on MMP-2.

Description (简体中文)

Application
ARP 101 is a MMP-2 selective inhibitor. ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development, and embryogenesis.
Biochem/physiol Actions
ARP 101 is a MMP-2 selective inhibitor (Gelatinase A, EC 3.4.24.24; TBE-1; LG4A; MONA; Type IV Collagenase). ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development and embryogenesis. IC50 = 0.81 nM on MMP-2.