Desloratadine

• Catalog No.: D1069
• CAS Number: 100643-71-8
• M. F.: C19H19ClN2
• M. W.: 310.82056
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(15),3(8),4,6,11,13-hexaene
• IUPAC Traditional name: clarinex
• Synonyms: Clarinex®; 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine

DATABASE IDS

• CAS Number: 100643-71-8
• MDL Number: MFCD00871949

PROPERTIES

• Empirical Formula (Hill Notation): C19H19ClN2
• Purity: ≥98% (HPLC)
• Apperance: powder
• Solubility: DMSO: >10 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
Legal Information
Clarinex is a registered trademark of Schering Corp.

Description (简体中文)

Biochem/physiol Actions
Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
法律信息
Clarinex 注册商标 Schering Corp.