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Ropinirole hydrochloride_Molecular_structure_CAS_91374-20-8)
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Ropinirole hydrochloride

Catalog No. R2530 Name Sigma Aldrich
CAS Number 91374-20-8 Website http://www.sigmaaldrich.com
M. F. C16H25ClN2O Telephone 1-800-521-8956
M. W. 296.8355 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 153991

SYNONYMS

IUPAC name
4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one hydrochloride
IUPAC Traditional name
ropinirole hydrochloride
Synonyms
4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride
SKF 101468 hydrochloride

DATABASE IDS

CAS Number 91374-20-8
MDL Number MFCD01754173

PROPERTIES

Empirical Formula (Hill Notation) C16H24N2O · HCl
Purity ≥98% (HPLC)
Apperance light yellow powder
Solubility H2O: >10 mg/mL
GHS Pictograms GHS07
GHS Pictograms GHS09
GHS Signal Word Warning
GHS Hazard statements H302-H400
European Hazard Symbols Harmful Harmful (Xn)
European Hazard Symbols Nature polluting Nature polluting (N)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P273
RID/ADR UN 3077 9/PG 3
Risk Statements 22-50/53
RTECS NM3288250
Safety Statements 36-60-61
Storage Temperature room temp
Hazard Class 9
UN Number 3077
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.
Description (简体中文)
Biochem/physiol Actions
An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.

REFERENCES