Ropinirole hydrochloride

• Catalog No.: R2530
• CAS Number: 91374-20-8
• M. F.: C16H25ClN2O
• M. W.: 296.8355
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one hydrochloride
• IUPAC Traditional name: ropinirole hydrochloride
• Synonyms: 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride; SKF 101468 hydrochloride

DATABASE IDS

• CAS Number: 91374-20-8
• MDL Number: MFCD01754173

PROPERTIES

• Empirical Formula (Hill Notation): C16H24N2O · HCl
• Purity: ≥98% (HPLC)
• Apperance: light yellow powder
• Solubility: H2O: >10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H400
• European Hazard Symbols: Harmful (Xn)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P273
• RID/ADR: UN 3077 9/PG 3
• Risk Statements: 22-50/53
• RTECS: NM3288250
• Safety Statements: 36-60-61
• Storage Temperature: room temp
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.

Description (简体中文)

Biochem/physiol Actions
An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.