BAY R3401

• Catalog No.: B3936
• CAS Number: 100276-03-7
• M. F.: C20H22ClNO4
• M. W.: 375.84598
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: propan-2-yl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1H,4H,5H,7H-furo[3,4-b]pyridine-3-carboxylate
• IUPAC Traditional name: isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-4H,7H-furo[3,4-b]pyridine-3-carboxylate
• Synonyms: 4-(2-Chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylic acid isopropyl ester

DATABASE IDS

• CAS Number: 100276-03-7
• MDL Number: MFCD08705409
• PubChem SID: 24891741

PROPERTIES

• Empirical Formula (Hill Notation): C20H22ClNO4
• Purity: ≥98% (HPLC)
• Apperance: white solid
• Solubility: DMSO: soluble15 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
Light sensitive; store in amber vials.
Biochem/physiol Actions
BAY R3401 is a glycogen phosphorylase inhibitor. The racemic prodrug, BAY R3401, suppresses hepatic glycogenolysis. BAY W1807, the active metabolite of BAY R3401, inhibits muscle glycogen phosphorylase a and b. It has been investigated that the metabolites of BAY R3401 suppress hepatic glycogenolysis by allosteric inhibition and dephosphorylation of phosphorylase a.

Description (简体中文)

包装
Light sensitive; store in amber vials.
Biochem/physiol Actions
BAY R3401 is a glycogen phosphorylase inhibitor. The racemic prodrug, BAY R3401, suppresses hepatic glycogenolysis. BAY W1807, the active metabolite of BAY R3401, inhibits muscle glycogen phosphorylase a and b. It has been investigated that the metabolites of BAY R3401 suppress hepatic glycogenolysis by allosteric inhibition and dephosphorylation of phosphorylase a.