Ifosfamide

• Catalog No.: I4909
• CAS Number: 3778-73-2
• M. F.: C7H15Cl2N2O2P
• M. W.: 261.085961
• Purity: ≥98%

SYNONYMS

• IUPAC name: 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2λ^5-oxazaphosphinan-2-one
• IUPAC Traditional name: ifosfamide
• Synonyms: N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide; Ifex

DATABASE IDS

• CAS Number: 3778-73-2
• EC Number: 223-237-3
• MDL Number: MFCD00057374

PROPERTIES

• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H319
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25-36
• RTECS: RP6050000
• Safety Statements: 26-45
• Storage Temperature: 2-8°C
• Empirical Formula (Hill Notation): C7H15Cl2N2O2P
• Purity: ≥98%
• Shipped in: wet ice

DETAILS

Description (English)

Biochem/physiol Actions
Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.

Description (简体中文)

Biochem/physiol Actions
Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.