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L-β-threo-benzyl-aspartate ammonium salt_Molecular_structure_CAS_871123-98-7(freeacid))
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L-β-threo-benzyl-aspartate ammonium salt

Catalog No. B6436 Name Sigma Aldrich
CAS Number 871123-98-7(freeacid) Website http://www.sigmaaldrich.com
M. F. C11H16N2O4 Telephone 1-800-521-8956
M. W. 240.25574 Fax
Purity ≥98% (HPLC) Email
Storage desiccated Chembase ID: 153976

SYNONYMS

Title
L-β-threo-benzyl-aspartate
IUPAC name
(2S,3S)-2-amino-3-benzylbutanedioic acid amine
IUPAC Traditional name
(2S,3S)-2-amino-3-benzylbutanedioic acid amine
Synonyms
(2S,3S)-2-Amino-3-benzylsuccinic ammonium salt
(2S,3S)-2-Amino-3-benzylsuccinic acid
DL-TBOA

DATABASE IDS

CAS Number 871123-98-7(freeacid)

PROPERTIES

Empirical Formula (Hill Notation) C11H13NO4 · xNH3
Purity ≥98% (HPLC)
Apperance white solid
Solubility H2O: >10 mg/mL
MSDS Link Download
Storage Condition desiccated
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
L-β-threo-benzyl-aspartate is a preferential EAAT3 excitatory amino acid transporter antagonist. The product exhibits 10-fold selectivity for EAAT3, Ki = 0.8 μM for EAAT3 in C17.2 neuroprogenitor cells expressing hEAATs (vs. Ki of 8.7 μM for EAAT1 and Ki of 10 μM for EAAT2). L-β-threo-benzyl-aspartate is a useful tool for studying the EAAT2 pharmacophore.
Description (简体中文)
Biochem/physiol Actions
L-β-threo-benzyl-aspartate is a preferential EAAT3 excitatory amino acid transporter antagonist. The product exhibits 10-fold selectivity for EAAT3, Ki = 0.8 μM for EAAT3 in C17.2 neuroprogenitor cells expressing hEAATs (vs. Ki of 8.7 μM for EAAT1 and Ki of 10 μM for EAAT2). L-β-threo-benzyl-aspartate is a useful tool for studying the EAAT2 pharmacophore.

REFERENCES