[6]-Gingerol

• Catalog No.: G1046
• CAS Number: 23513-14-6
• M. F.: C17H26O4
• M. W.: 294.38594
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• Title: 6-姜酚
• IUPAC name: (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one
• IUPAC Traditional name: gingerol
• Synonyms: 6-Gingerol; 姜辣素; 3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-; 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; 5-羟基-1-(4-羟基-3-甲氧基苯基)-3-癸酮; 6-姜辣醇

DATABASE IDS

• CAS Number: 23513-14-6
• MDL Number: MFCD00210507

PROPERTIES

• Risk Statements: 22-36/37/38
• RTECS: HE0757000
• Safety Statements: 26-36/37
• Storage Condition: protect from light
• Storage Condition: under inert gas
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Empirical Formula (Hill Notation): C17H26O4
• Purity: ≥98% (HPLC)
• Shipped in: dry ice
• Solubility: methanol: soluble1 mg/mL, clear, colorless

DETAILS

Description (English)

Biochem/physiol Actions
Bioactive compound found in ginger (Zingiber officinale) with antioxidant activity,1 which functions as an anti-inflammatory and antitumor agent. [6]-Gingerol down regulates proinflammatory cytokine release by macrophages.2 It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin.3
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. G1046.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

Biochem/physiol Actions
存在于生姜 (Zingiber officinale) 中的具有抗氧化活性的生物活性化合物，1可用作抗炎剂和抗肿瘤剂。6-姜酚通过巨噬细胞下调促炎细胞因子的释放。2已证明它可通过阻断经佛波酯刺激的小鼠皮肤中 p38 MAP 激酶和 NF-κB 的活化来抑制 COX-2 的表达。3
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. G1046.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.