Venlafaxine hydrochloride

• Catalog No.: V7264
• CAS Number: 99300-78-4
• M. F.: C17H28ClNO2
• M. W.: 313.86272
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• Title: Venlafaxine 盐酸盐
• IUPAC name: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol hydrochloride
• IUPAC Traditional name: venlafaxine hydrochloride
• Synonyms: Effexor; (+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride

DATABASE IDS

• CAS Number: 99300-78-4
• MDL Number: MFCD03658865

PROPERTIES

• Empirical Formula (Hill Notation): C17H27NO2 · HCl
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: H2O: >10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H319
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 36
• RTECS: GV8872760
• Safety Statements: 26
• Storage Condition: protect from light
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.

Description (简体中文)

Biochem/physiol Actions
Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.