Nateglinide

• Catalog No.: N3538
• CAS Number: 105816-04-4
• M. F.: C19H27NO3
• M. W.: 317.42258
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid
• IUPAC Traditional name: nateglinide
• Synonyms: Starsis; N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine; Fastic; Starlix

DATABASE IDS

• CAS Number: 105816-04-4
• MDL Number: MFCD00875706

PROPERTIES

• Empirical Formula (Hill Notation): C19H27NO3
• Purity: ≥98% (HPLC)
• Apperance: white to off-white solid
• Solubility: DMSO: >5 mg/mL
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: SQ7318950
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Nateglinide is a Kir6.2/SUR1 channel inhibitor and antidiabetic. It is selective for the SUR1 subtype, which is found on pancreatic islet cells. Nateglinide evokes KATP channel-dependent insulin secretion (50-200 μM) in the absence and presence of insulin.

Description (简体中文)

Biochem/physiol Actions
Nateglinide is a Kir6.2/SUR1 channel inhibitor and antidiabetic. It is selective for the SUR1 subtype, which is found on pancreatic islet cells. Nateglinide evokes KATP channel-dependent insulin secretion (50-200 μM) in the absence and presence of insulin.