Borrelidin

• Catalog No.: B1936
• CAS Number: 7184-60-3
• M. F.: C28H43NO6
• M. W.: 489.64412
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: (1R,2R)-2-[(2S,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid
• IUPAC Traditional name: (1R,2R)-2-[(2S,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid
• Synonyms: Borrelidine; NSC 216128; Treponemycin; 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecarboxylic acid; Cyclopentanecarboxylic acid

DATABASE IDS

• MDL Number: MFCD01740784
• CAS Number: 7184-60-3
• PubChem SID: 24724413

PROPERTIES

• Biological Source: from Streptomyces sp.
• Empirical Formula (Hill Notation): C28H43NO6
• Purity: ≥95% (HPLC)
• Apperance: lyophilized powder
• Solubility: DMF: soluble
• Solubility: DMSO: soluble
• Solubility: ethanol: soluble
• Solubility: ethyl acetate: soluble
• Solubility: methanol: soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: ED8750000
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Borrelidin is a potent angiogenesis inhibitor that induces apoptosis in capillary tube-forming cells. Also displays antimalarial activity against drug-resistant Plasmodia. Antimicrobial and selective threonyl t-RNA synthetase inhibitor.

Description (简体中文)

Biochem/physiol Actions
Borrelidin is a potent angiogenesis inhibitor that induces apoptosis in capillary tube-forming cells. Also displays antimalarial activity against drug-resistant Plasmodia. Antimicrobial and selective threonyl t-RNA synthetase inhibitor.