Fulvestrant

• Catalog No.: I4409
• CAS Number: 129453-61-8
• M. F.: C32H47F5O3S
• M. W.: 606.770796
• Purity: >98% (HPLC)

SYNONYMS

• IUPAC name: (1S,9R,10R,11S,14S,15S)-15-methyl-9-[9-(4,4,5,5,5-pentafluoropentanesulfinyl)nonyl]tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-triene-5,14-diol
• IUPAC Traditional name: fulvestrant
• Synonyms: Faslodex; ZD 9238; ZD 182780; ICI 182,780; (7a,17b)-7-[9-[(4,4,5,5,5pentafluoropentyl)Sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol; ZM 182780

DATABASE IDS

• MDL Number: MFCD00903953
• CAS Number: 129453-61-8

PROPERTIES

• Empirical Formula (Hill Notation): C32H47F5O3S
• Purity: >98% (HPLC)
• Apperance: powder
• Solubility: DMSO: >5 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: KG7623000
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Fulvestrant (ICI 182,780) is a selective estrogen receptor down-regulator (SERD). Fulvestrant is a high affinity estrogen receptor antagonist. IC50 = 0.29 nM. Fulvestrant is the first "pure" antiestrogen with no agonistic activity both in vitro and in vivo.

Description (简体中文)

Biochem/physiol Actions
Fulvestrant (ICI 182,780) is a selective estrogen receptor down-regulator (SERD). Fulvestrant is a high affinity estrogen receptor antagonist. IC50 = 0.29 nM. Fulvestrant is the first "pure" antiestrogen with no agonistic activity both in vitro and in vivo.