PRL-3 Inhibitor I

• Catalog No.: P0108
• CAS Number: 893449-38-2
• M. F.: C17H11Br2NO2S2
• M. W.: 485.21274
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• IUPAC name: 5-({5-bromo-2-[(2-bromophenyl)methoxy]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
• IUPAC Traditional name: 5-({5-bromo-2-[(2-bromophenyl)methoxy]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
• Synonyms: 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone; Phosphatase of regenerating liver-3, Inhibitor I

DATABASE IDS

• MDL Number: MFCD11045303
• CAS Number: 893449-38-2

PROPERTIES

• Empirical Formula (Hill Notation): C17H11Br2NO2S2
• Purity: ≥98% (HPLC)
• Apperance: yellow solid
• Solubility: DMSO: >10 mg/mL
• Solubility: H2O: <2 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335-H410
• European Hazard Symbols: Irritant (Xi)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P273-P305 + P351 + P338-P501
• RID/ADR: UN 3077 9/PG 3
• Risk Statements: 36/37/38-50/53
• Safety Statements: 26-36/37-60-61
• Storage Condition: protect from light
• Storage Temperature: -20°C
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
PRL-3 Inhibitor I is a rhodanine derivative with an IC50 value of 0.9 μM against phosphatase of regenerating liver-3 (PRL-3), a nonclassical protein tyrosine phosphatase that has recently been shown to be involved in cancer metastasis. PRL-3 Inhibitor I reduced the invasiveness of B16F10 melanoma cells in a cell based assay.

Description (简体中文)

Biochem/physiol Actions
PRL-3 Inhibitor I is a rhodanine derivative with an IC50 value of 0.9 μM against phosphatase of regenerating liver-3 (PRL-3), a nonclassical protein tyrosine phosphatase that has recently been shown to be involved in cancer metastasis. PRL-3 Inhibitor I reduced the invasiveness of B16F10 melanoma cells in a cell based assay.