6β-Naltrexol hydrate

• Catalog No.: N9412
• M. F.: C20H27NO5
• M. W.: 361.43208
• Purity: ≥96% (HPLC)

SYNONYMS

• IUPAC name: (1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,14,17-triol hydrate
• IUPAC Traditional name: (1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,14,17-triol hydrate
• Synonyms: (5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol hydrate

DATABASE IDS

• MDL Number: MFCD08277038
• PubChem SID: 24724560

PROPERTIES

• Empirical Formula (Hill Notation): C20H25NO4 · xH2O
• Purity: ≥96% (HPLC)
• Apperance: white powder
• Solubility: DMSO: ~12 mg/mL
• Solubility: H2O: insoluble
• Drug Control: regulated under CDSA - not available from Sigma-Aldrich Canada
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Neutral antagonist of the μ-opioid receptor. A reduction of withdrawal effects associated with neutral μ-opioid receptor antagonists may offer advantages in treating opioid overdose and addiction.

Description (简体中文)

Biochem/physiol Actions
Neutral antagonist of the μ-opioid receptor. A reduction of withdrawal effects associated with neutral μ-opioid receptor antagonists may offer advantages in treating opioid overdose and addiction.