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Salvinorin A

Catalog No. S8071 Name Sigma Aldrich
CAS Number 83729-01-5 Website http://www.sigmaaldrich.com
M. F. C23H28O8 Telephone 1-800-521-8956
M. W. 432.46362 Fax
Purity ≥98% (HPLC) Email
Storage protect from light Chembase ID: 129366

SYNONYMS

IUPAC name
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro-1H-naphtho[2,1-c]pyran-7-carboxylate
IUPAC Traditional name
salvinorin A
Synonyms
(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester

DATABASE IDS

MDL Number MFCD05664742
PubChem SID 24899776
CAS Number 83729-01-5

PROPERTIES

Empirical Formula (Hill Notation) C23H28O8
Purity ≥98% (HPLC)
Gene Information human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)rat ... Oprk1(29335)
Apperance white film
Solubility DMSO: ≥10 mg/mL
Solubility ethanol: ~3 mg/mL
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS QL6127142
Storage Condition protect from light
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.
Description (简体中文)
Biochem/physiol Actions
Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

REFERENCES