Lercanidipine hydrochloride hemihydrate

• Catalog No.: L6668
• CAS Number: 132866-11-6(anhydrous)
• M. F.: C70H82Cl2N6O13
• M. W.: 1286.33848
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• Title: Lercanidipine 盐酸盐
• IUPAC name: bis(5-{1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl} 3-methyl 2-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) hydrate dihydrochloride
• IUPAC Traditional name: bis(5-{1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl} 3-methyl 2-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) hydrate dihydrochloride

DATABASE IDS

• PubChem SID: 24724527
• CAS Number: 132866-11-6(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C36H41N3O6 · HCl · 0.5H2O
• Purity: ≥98% (HPLC)
• Apperance: yellow powder
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 36/37-45
• Storage Condition: desiccated
• Storage Condition: protect from light
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonistvoltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine .

Description (简体中文)

Biochem/physiol Actions
Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonistvoltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine .