Biperiden hydrochloride

• Catalog No.: B5311
• CAS Number: 1235-82-1
• M. F.: C21H30ClNO
• M. W.: 347.922
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: Biperiden 盐酸盐
• IUPAC name: 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
• IUPAC Traditional name: biperiden hydrochloride
• Synonyms: Akinophyl; Akineton; 1-(5-Bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-(1-piperidinyl)propan-1-ol hydrochloride

DATABASE IDS

• CAS Number: 1235-82-1
• EC Number: 214-976-2

PROPERTIES

• Empirical Formula (Hill Notation): C21H30ClNO
• Purity: ≥98% (HPLC)
• Apperance: off-white powder
• Solubility: DMSO: >20 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H319
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 22
• RTECS: TN3706000
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD50 in rats 750 mg/kg; in dogs 340 mg/kg.

Description (简体中文)

Biochem/physiol Actions
Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD50 in rats 750 mg/kg; in dogs 340 mg/kg.