Levetiracetam

• Catalog No.: L8668
• CAS Number: 102767-28-2
• M. F.: C8H14N2O2
• M. W.: 170.20896
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (2S)-2-(2-oxopyrrolidin-1-yl)butanamide
• IUPAC Traditional name: levetiracetam
• Synonyms: (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetamide; Keppra®; 2(S)-(2-oxopyrrolidin-1-yl)butyramide

DATABASE IDS

• CAS Number: 102767-28-2
• MDL Number: MFCD03265610

PROPERTIES

• Empirical Formula (Hill Notation): C8H14N2O2
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: H2O: >5 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H319
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 22-36
• RTECS: UX9656166
• Safety Statements: 26
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.

Description (简体中文)

Biochem/physiol Actions
Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.
法律信息
Keppra 注册商标 UCB Pharma, S.A.