Amthamine dihydrobromide

• Catalog No.: A4730
• CAS Number: 142457-00-9
• M. F.: C6H13Br2N3S
• M. W.: 319.06052
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrobromide
• IUPAC Traditional name: amthamine dihydrobromide
• Synonyms: 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide

DATABASE IDS

• MDL Number: MFCD00673891
• CAS Number: 142457-00-9
• PubChem SID: 24890905

PROPERTIES

• Empirical Formula (Hill Notation): C6H11N3S · 2HBr
• Purity: ≥98% (HPLC)
• Apperance: off-white solid
• Solubility: H2O: soluble27 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Amthamine dihydrobromide is a histamine H2 receptor agonist. Amthamine dihydrobromide has been used to study the effect of mast cells on T regulatory cell function.
Biochem/physiol Actions
Amthamine dihydrobromide is a H2 histamine receptor agonist. Amthamine dihydrobromide, similar to histamine, inhibits H2 receptor-mediated eosinophil peroxidase (EPO) release with IC50 = 0.4 μM; a weak antagonist at H3 and shows no activity at H1 receptors.

Description (简体中文)

Application
Amthamine dihydrobromide is a histamine H2 receptor agonist. Amthamine dihydrobromide has been used to study the effect of mast cells on T regulatory cell function.
Biochem/physiol Actions
Amthamine dihydrobromide is a H2 histamine receptor agonist. Amthamine dihydrobromide, similar to histamine, inhibits H2 receptor-mediated eosinophil peroxidase (EPO) release with IC50 = 0.4 μM; a weak antagonist at H3 and shows no activity at H1 receptors.