DCP-LA

• Catalog No.: D5318
• CAS Number: 28399-31-7
• M. F.: C20H36O2
• M. W.: 308.49864
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: 8-{2-[(2-pentylcyclopropyl)methyl]cyclopropyl}octanoic acid
• IUPAC Traditional name: 8-{2-[(2-pentylcyclopropyl)methyl]cyclopropyl}octanoic acid
• Synonyms: 2-[(2-pentylcyclopropyl)methyl]cyclopropaneoctanoic acid; 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid; FR 236924

DATABASE IDS

• MDL Number: MFCD09265251
• PubChem SID: 24724463
• CAS Number: 28399-31-7

PROPERTIES

• Empirical Formula (Hill Notation): C20H36O2
• Purity: ≥95% (HPLC)
• Apperance: clear oil
• Solubility: DMSO: >2 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
DCP-LA is a selective PKC-epsilon (PKC-ε) activator. In the in situ PKC assay with a reversed phase high-performance liquid chromatography, DCP-LA significantly activated PKC in PC-12 cells in a concentration (10 nM-100 μM)-dependent manner, with the maximal effect at 100 nM. DCP-LA has over a 7-fold greater potency for activation of PKC-ε over other PKC isozymes.

Description (简体中文)

Biochem/physiol Actions
DCP-LA is a selective PKC-epsilon (PKC-ε) activator. In the in situ PKC assay with a reversed phase high-performance liquid chromatography, DCP-LA significantly activated PKC in PC-12 cells in a concentration (10 nM-100 μM)-dependent manner, with the maximal effect at 100 nM. DCP-LA has over a 7-fold greater potency for activation of PKC-ε over other PKC isozymes.