Eliprodil

• Catalog No.: E2031
• CAS Number: 119431-25-3
• M. F.: C20H23ClFNO
• M. W.: 347.8541232
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol
• IUPAC Traditional name: eliprodil
• Synonyms: SL 820715; α-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol

DATABASE IDS

• MDL Number: MFCD00866651
• PubChem SID: 24277709
• CAS Number: 119431-25-3

PROPERTIES

• Empirical Formula (Hill Notation): C20H23ClFNO
• Purity: ≥98% (HPLC)
• Gene Information: human ... GRIN2B(2904)rat ... Adra1a(29412)
• Apperance: white solid
• Solubility: DMSO: ~17 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H319-H410
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: Eyeshields, Gloves
• GHS Precautionary statements: P273-P305 + P351 + P338-P501
• RID/ADR: UN 3077 9/PG 3
• Risk Statements: 50/53
• Safety Statements: 60-61
• Storage Temperature: 2-8°C
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
NR2B selective NMDA glutamate receptor antagonist which appears to target the "polyamine site" on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain.

Description (简体中文)

Biochem/physiol Actions
NR2B selective NMDA glutamate receptor antagonist which appears to target the "polyamine site" on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain.