ABT-491 hydrochloride

• Catalog No.: A9227
• CAS Number: 189689-94-9
• M. F.: C28H23ClFN5O2
• M. W.: 515.9659232
• Purity: >99% (HPLC)

SYNONYMS

• IUPAC name: 4-ethynyl-3-[3-fluoro-4-({2-methyl-1H-imidazo[4,5-c]pyridin-1-yl}methyl)benzoyl]-N,N-dimethyl-1H-indole-1-carboxamide hydrochloride
• IUPAC Traditional name: 4-ethynyl-3-[3-fluoro-4-({2-methylimidazo[4,5-c]pyridin-1-yl}methyl)benzoyl]-N,N-dimethylindole-1-carboxamide hydrochloride
• Synonyms: 4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride; A-137491

DATABASE IDS

• CAS Number: 189689-94-9
• PubChem SID: 24724404
• MDL Number: MFCD00945301

PROPERTIES

• Empirical Formula (Hill Notation): C28H22N5O2F · HCl
• Purity: >99% (HPLC)
• Apperance: white
• Melting Point: 170-178 °C(lit.)
• Solubility: H2O: freely soluble22 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Highly potent, selective and orally active platelet-activating factor (PAF) receptor antagonist. Ki = 0.6 nM in human platelets.

Description (简体中文)

Biochem/physiol Actions
Highly potent, selective and orally active platelet-activating factor (PAF) receptor antagonist. Ki = 0.6 nM in human platelets.