SB 202190

• Catalog No.: S7067
• CAS Number: 152121-30-7
• M. F.: C20H14FN3O
• M. W.: 331.3430632
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
• IUPAC Traditional name: 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
• Synonyms: 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole

DATABASE IDS

• PubChem SID: 24278272
• CAS Number: 152121-30-7
• MDL Number: MFCD00941964

PROPERTIES

• Empirical Formula (Hill Notation): C20H14FN3O
• Purity: ≥98% (HPLC)
• Gene Information: human ... MAPK14(1432)
• Apperance: pale yellow
• Solubility: DMSO: soluble30 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
SB 202190 is a highly selective, potent and cell permeable inhibitor of p38 MAP kinase. SB 202190 binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

Description (简体中文)

Biochem/physiol Actions
SB 202190 is a highly selective, potent and cell permeable inhibitor of p38 MAP kinase. SB 202190 binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline