Asn-Arg-Cys-Ser-Gln-Gly-Ser-Cys-Trp-Asn, Reduced_Molecular_structure_CAS_)

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Asn-Arg-Cys-Ser-Gln-Gly-Ser-Cys-Trp-Asn, Reduced
Catalog No.	A2602	Name	Sigma Aldrich
CAS Number		Website	http://www.sigmaaldrich.com
M. F.	C44H67N17O16S2	Telephone	1-800-521-8956
M. W.	1154.23708	Fax
Purity	≥85% (HPLC)	Email
Storage		Chembase ID: 153796

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SYNONYMS

IUPAC name

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-5-carbamimidamidopentanamido]-3-sulfanylpropanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]acetamido}-3-hydroxypropanamido]-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanamido]-3-carbamoylpropanoic acid

IUPAC Traditional name

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-5-carbamimidamidopentanamido]-3-sulfanylpropanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]acetamido}-3-hydroxypropanamido]-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanamido]-3-carbamoylpropanoic acid

DATABASE IDS

MDL Number

MFCD00798787

PROPERTIES

Empirical Formula (Hill Notation)	C44H67N17O16S2
Purity	≥85% (HPLC)
MSDS Link	Download
Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature	-20°C
German water hazard class	3

DETAILS

Description (English)

Amino Acid Sequence
Asn-Arg-Cys-Ser-Gln-Gly-Ser-Cys-Trp-Asn
Biochem/physiol Actions
The activity of the enzymes protein disulfide-isomerase (PDI) and DsbA (a periplasmic protein thiol:disulfide oxidoreductase) can be monitored with this peptide. Oxidation of this dithiol peptide to the disulfide state is accompanied by a significant change in tryptophan fluorescence emission intensity. This permits the rapid determination of the pH-dependence of the activity of both enzymes.

Description (简体中文)