Ampicillin sodium salt

• Catalog No.: A8351
• CAS Number: 69-52-3
• M. F.: C16H18N3NaO4S
• M. W.: 371.38659

SYNONYMS

• Title: 氨苄西林 钠盐
• IUPAC name: sodium (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• IUPAC Traditional name: sodium ampicillin(1-)
• Synonyms: D-(-)-α-Aminobenzylpenicillin sodium salt; 氨苄青霉素 钠盐

DATABASE IDS

• MDL Number: MFCD00064313
• PubChem SID: 24891335
• EC Number: 200-708-1
• Beilstein Number: 4119211
• CAS Number: 69-52-3

PROPERTIES

• Empirical Formula (Hill Notation): C16H18N3NaO4S
• Impurities: endotoxin, tested
• Product Line: BioXtra
• Suitability: suitable for cell culture
• Melting Point: 215 °C (dec.)(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H317-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P342 + P311
• Risk Statements: 42/43
• RTECS: XH8400000
• Safety Statements: 22-36/37-45
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Application
Used to select for ampicillin resistance in mutated and transformed cells.
Biochem/physiol Actions
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Description (简体中文)

Application
Used to select for ampicillin resistance in mutated and transformed cells.
Biochem/physiol Actions
β-内酰胺类抗生素，具有连接到青霉素结构上的氨基侧链。青霉素衍生物，通过灭活细菌细胞膜内表面上的转肽酶，抑制细菌细胞壁的合成（肽聚糖交联）。仅对生长的 Escherichia coli 具有杀菌作用。抗性方式：通过 β-内酰胺酶使氨苄西林的 β-内酰胺环分裂。抗菌谱：革兰氏阴性和革兰氏阳性细菌。
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information