Gö 6983

• Catalog No.: G1918
• CAS Number: 133053-19-7
• M. F.: C26H26N4O3
• M. W.: 442.50964
• Purity: ≥97%

SYNONYMS

• IUPAC name: 3-{1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
• IUPAC Traditional name: 3-{1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
• Synonyms: 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

DATABASE IDS

• PubChem SID: 24894916
• MDL Number: MFCD04040031
• CAS Number: 133053-19-7

PROPERTIES

• Empirical Formula (Hill Notation): C26H26N4O3
• Purity: ≥97%
• Apperance: red powder
• Solubility: DMSO: ≥20 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Protein kinase C (PKC) inhibitor that selectively inhibits several PKC isozymes (IC50 = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ), but does not inhibit PKCμ (IC50 = 20 mM).

Description (简体中文)

Biochem/physiol Actions
Protein kinase C (PKC) inhibitor that selectively inhibits several PKC isozymes (IC50 = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ), but does not inhibit PKCμ (IC50 = 20 mM).