Kenpaullone

• Catalog No.: K3888
• CAS Number: 142273-20-9
• M. F.: C16H11BrN2O
• M. W.: 327.17534
• Purity: ≥99%

SYNONYMS

• IUPAC name: 14-bromo-8,18-diazatetracyclo[9.7.0.0^2,^7.0^1^2,^1^7]octadeca-1(11),2,4,6,12,14,16-heptaen-9-one
• IUPAC Traditional name: 14-bromo-8,18-diazatetracyclo[9.7.0.0^2,^7.0^1^2,^1^7]octadeca-1(11),2,4,6,12,14,16-heptaen-9-one
• Synonyms: 9-Bromo-7,12-dihydro-indolo-[3,2-d]-[1]benzazepin-6(5H)-one; NSC 664704

DATABASE IDS

• PubChem SID: 24278507
• MDL Number: MFCD02683595
• CAS Number: 142273-20-9

PROPERTIES

• Empirical Formula (Hill Notation): C16H11BrN2O
• Purity: ≥99%
• Gene Information: human ... CDC2(983)mouse ... Gsk3b(56637)rat ... Gsk3b(84027)
• Apperance: yellow
• Solubility: DMSO: soluble18 mg/mL, clear, yellow
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM).
Packaging
Store under argon

Description (简体中文)

Biochem/physiol Actions
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM).
包装
Store under argon