MDL 28170

• Catalog No.: M6690
• CAS Number: 88191-84-8
• M. F.: C22H26N2O4
• M. W.: 382.45284
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: benzyl N-[(1S)-2-methyl-1-[(1-oxo-3-phenylpropan-2-yl)carbamoyl]propyl]carbamate
• IUPAC Traditional name: benzyl N-[(1S)-2-methyl-1-[(1-oxo-3-phenylpropan-2-yl)carbamoyl]propyl]carbamate
• Synonyms: Calpain Inhibitor III

DATABASE IDS

• PubChem SID: 24278565
• CAS Number: 88191-84-8
• MDL Number: MFCD00798796

PROPERTIES

• Compostion: Peptide Content, >90%
• Empirical Formula (Hill Notation): C22H26N2O4
• Purity: ≥95% (HPLC)
• Shipped in: wet ice
• Gene Information: human ... CAPN1(823), CAPN2(824)
• Solubility: DMSO: soluble26 mg/mL
• Solubility: H2O: insoluble
• Solubility: methanol: soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Z-Val-Phe-al
Biochem/physiol Actions
MDL 28170 is a potent cell permeable calpain I and II inhibitor; reduces capsaicin-mediated cell death in cultured dorsal root ganglion neurons. Reduced occurrence of apoptosis in H2O2 and A23187 treated PC12 cells. γ-secretase-inhibitor.

Description (简体中文)

Amino Acid Sequence
Z-Val-Phe-al
Biochem/physiol Actions
MDL 28170 is a potent cell permeable calpain I and II inhibitor; reduces capsaicin-mediated cell death in cultured dorsal root ganglion neurons. Reduced occurrence of apoptosis in H2O2 and A23187 treated PC12 cells. γ-secretase-inhibitor.