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AM251

Catalog No. A6226 Name Sigma Aldrich
CAS Number 183232-66-8 Website http://www.sigmaaldrich.com
M. F. C22H21Cl2IN4O Telephone 1-800-521-8956
M. W. 555.23881 Fax
Purity >98% (HPLC) Email
Storage Chembase ID: 125776

SYNONYMS

IUPAC name
1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
IUPAC Traditional name
1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)pyrazole-3-carboxamide
Synonyms
1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide

DATABASE IDS

MDL Number MFCD01861181
PubChem SID 24891069
CAS Number 183232-66-8

PROPERTIES

Empirical Formula (Hill Notation) C22H21N4OCl2I
Purity >98% (HPLC)
Gene Information mouse ... Cnr1(12801), Cnr2(12802)rat ... Cnr1(25248)
Apperance white solid
Solubility DMSO: >10 mg/mL
Solubility H2O: insoluble
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
AM251 is a CB1 cannabinoid receptor antagonist.
Other Notes
Salt content may vary.
Application
AM251, a CB1 cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.
Description (简体中文)
Biochem/physiol Actions
AM251 is a CB1 cannabinoid receptor antagonist.
Other Notes
Salt content may vary.
Application
AM251, a CB1 cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.

REFERENCES