Ranolazine dihydrochloride

• Catalog No.: R6152
• CAS Number: 95635-56-6
• M. F.: C24H35Cl2N3O4
• M. W.: 500.4584
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide dihydrochloride
• IUPAC Traditional name: ranolazine dihydrochloride
• Synonyms: (±) -4-[2-Hydroxy-3-(o-methoxyphenoxy)propyl]-1-piperazineaceto-2′,6′-xylidide dihydrochloride; N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride

DATABASE IDS

• MDL Number: MFCD03788770
• PubChem SID: 24278795
• CAS Number: 95635-56-6

PROPERTIES

• Empirical Formula (Hill Notation): C24H33N3O4 · 2HCl
• Purity: ≥98% (HPLC)
• Apperance: white to beige powder
• Melting Point: 222-229.5 °C(lit.)
• Solubility: H2O: soluble ≥10 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
pFOX (partial fatty acid oxidation) inhibitor, a new class of anti-anginal drugs, which inhibit fatty acid beta-oxidation and activates pyruvate dehydrogenase, thereby diverting the heart′s energy source from lipids to glucose, which requires less oxygen and helps maintain myocardiac function at times of ischemia

Description (简体中文)

Biochem/physiol Actions
pFOX (partial fatty acid oxidation) inhibitor, a new class of anti-anginal drugs, which inhibit fatty acid beta-oxidation and activates pyruvate dehydrogenase, thereby diverting the heart′s energy source from lipids to glucose, which requires less oxygen and helps maintain myocardiac function at times of ischemia