β-Nicotinamide adenine dinucleotide phosphate sodium salt

• Catalog No.: N8035
• CAS Number: 1184-16-3
• M. F.: C21H29N7NaO17P3
• M. W.: 767.402713

SYNONYMS

• Title: β-烟酰胺腺嘌呤二核苷酸磷酸 钠盐
• IUPAC name: sodium 1-[(3R,4S,5R)-5-({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-phosphonooxolan-2-yl]methyl phosphonato}oxy)phosphinato]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ^5-pyridin-1-ylium hydrate
• IUPAC Traditional name: sodium 1-[(3R,4S,5R)-5-{[({[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxolan-2-yl]methyl phosphonato}oxyphosphinato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ^5-pyridin-1-ylium hydrate
• Synonyms: Coenzyme II sodium salt; NADP; TPN-Na; Triphosphopyridine nucleotide sodium salt; β-NADP-Na; β-NADP-sodium salt; TPN; 三磷酸吡啶核苷酸 钠盐

DATABASE IDS

• MDL Number: MFCD00036973
• PubChem SID: 24897850
• EC Number: 214-664-6
• CAS Number: 1184-16-3
• Beilstein Number: 4779954

PROPERTIES

• Linear Formula: C21H27N7O17P3 · Na
• Packaging: pkg of 5 mg (per vial)
• Melting Point: 175-178 °C (dec.)(lit.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Electron acceptor
Other Notes
Packaged based on NADP content as determined by UV-Vis.
This is the common form of NADP. Do not confuse with 3′-NADP or α-NADP.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Description (简体中文)

Biochem/physiol Actions
Electron acceptor
Other Notes
Packaged based on NADP content as determined by UV-Vis.
This is the common form of NADP. Do not confuse with 3′-NADP or α-NADP.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).