Mdivi-1

• Catalog No.: M0199
• CAS Number: 338967-87-6
• M. F.: C15H10Cl2N2O2S
• M. W.: 353.2231
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one
• IUPAC Traditional name: 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylquinazolin-4-one
• Synonyms: 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone; 3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone

DATABASE IDS

• MDL Number: MFCD00974506
• CAS Number: 338967-87-6

PROPERTIES

• Empirical Formula (Hill Notation): C15H10Cl2N2O2S
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: powder
• Solubility: DMSO: >20 mg/mL
• RID/ADR: UN 2811 6.1/PG 3
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Mdivi-1 is a cell-permeable selective inhibitor of mitochondrial division DRP (dynamin-related GTPase) and inhibitor of the mitochondrial division dynamin (Dnm1). Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mdivi-1 is the first selective inhibitor of mitochondrial division dynamins. In principle, Mdivi-1 represents a class of therapeutics for stroke, myocardial infarction, and neurodegenerative diseases.

Description (简体中文)

Biochem/physiol Actions
Mdivi-1 is a cell-permeable selective inhibitor of mitochondrial division DRP (dynamin-related GTPase) and inhibitor of the mitochondrial division dynamin (Dnm1). Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mdivi-1 is the first selective inhibitor of mitochondrial division dynamins. In principle, Mdivi-1 represents a class of therapeutics for stroke, myocardial infarction, and neurodegenerative diseases.