FH535

• Catalog No.: F5682
• M. F.: C13H10Cl2N2O4S
• M. W.: 361.2005
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzene-1-sulfonamide
• IUPAC Traditional name: 2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide

DATABASE IDS

• MDL Number: MFCD01212888

PROPERTIES

• Empirical Formula (Hill Notation): C13H10Cl2N2O4S
• Purity: ≥98% (HPLC)
• Apperance: solid
• Solubility: DMSO: soluble20 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H318
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P280-P305 + P351 + P338
• Risk Statements: 41
• Safety Statements: 36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
FH535 is a reversible dual inhibitor of Wnt/β-catenin and a PPARγ and PPARδ signaling antagonist. FH535 is unique in its ability to inhibit the Wnt/β-catenin pathway. The compound is selectively toxic to some carcinomas expressing the Wnt/β-catenin pathway.

Description (简体中文)

Biochem/physiol Actions
FH535 is a reversible dual inhibitor of Wnt/β-catenin and a PPARγ and PPARδ signaling antagonist. FH535 is unique in its ability to inhibit the Wnt/β-catenin pathway. The compound is selectively toxic to some carcinomas expressing the Wnt/β-catenin pathway.