Rotigotine hydrochloride

• Catalog No.: R9281
• CAS Number: 99755-59-6
• M. F.: C19H26ClNOS
• M. W.: 351.93384
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
• IUPAC Traditional name: neupro hydrochloride
• Synonyms: (-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride; Neupro; SPM 962; (-)-N 0437; N 0923

DATABASE IDS

• MDL Number: MFCD00906149
• CAS Number: 99755-59-6

PROPERTIES

• Empirical Formula (Hill Notation): C19H25NOS·HCl
• Purity: ≥98% (HPLC)
• Apperance: white to off-white solid
• Solubility: DMSO: >10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• Storage Temperature: room temp
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.

Description (简体中文)

Biochem/physiol Actions
Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.