NIR-664-iodoacetamide

• Catalog No.: 12535
• CAS Number: 149021-66-9
• M. F.: C37H42IN3O4S
• M. W.: 751.71655
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: 2-(5-{5-[(2-iodoacetamido)methyl]-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-ylidene}penta-1,3-dien-1-yl)-1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-3-ium
• IUPAC Traditional name: 2-(5-{5-[(2-iodoacetamido)methyl]-1,3,3-trimethylindol-2-ylidene}penta-1,3-dien-1-yl)-1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium
• Synonyms: 4,5-Benzo-5′-(iodoacetaminomethyl)-1′,3,3,3′,3′-pentamethyl-1-(4-sulfobutyl)indodicarbocyanine

DATABASE IDS

• MDL Number: MFCD01862918
• PubChem SID: 24847661
• CAS Number: 149021-66-9

PROPERTIES

• Empirical Formula (Hill Notation): C37H42IN3O4S
• Purity: ≥90% (HPLC)
• Suitability: suitable for fluorescence
• Fluorescence: λex 664 nm; λem 689 nm in methanol
• Solubility: 1-hexanol: soluble
• Solubility: methanol: soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Cyanine label for derivatization of thiols6
Application
NIR-664-iodoacetamide, is a cyanine-based dye, which is a very efficient sensor of the chemical environment because of its strong fluorescence response to the hydrophobic nature of its immediate microenvironment 1. Such changes result in an altered equilibrium between the monomer and aggregate states of this dye, which are demonstrated by absorption peaks at 665 and 615 nm, respectively 2. A fluorescent dye which can be covalently encapsulated into silica nanoparticles to elucidate the internal architecture using the methods of fluorescence correlation spectroscopy and fluorescence lifetime measurements 3,2. This dye has a quantum efficiency of 23%, a molar absorptivity of 187,000 L mol-1 cm-1 4, and a small Stokes shift 5.

Description (简体中文)

Other Notes
Cyanine label for derivatization of thiols6
Application
NIR-664-iodoacetamide, is a cyanine-based dye, which is a very efficient sensor of the chemical environment because of its strong fluorescence response to the hydrophobic nature of its immediate microenvironment 1. Such changes result in an altered equilibrium between the monomer and aggregate states of this dye, which are demonstrated by absorption peaks at 665 and 615 nm, respectively 2. A fluorescent dye which can be covalently encapsulated into silica nanoparticles to elucidate the internal architecture using the methods of fluorescence correlation spectroscopy and fluorescence lifetime measurements 3,2. This dye has a quantum efficiency of 23%, a molar absorptivity of 187,000 L mol-1 cm-1 4, and a small Stokes shift 5.