Thiolactomycin

• Catalog No.: T9567
• CAS Number: 82079-32-1
• M. F.: C11H14O2S
• M. W.: 210.29266
• Purity: 98% (HPLC)

SYNONYMS

• IUPAC name: (5R)-4-hydroxy-3,5-dimethyl-5-(2-methylbuta-1,3-dien-1-yl)-2,5-dihydrothiophen-2-one
• IUPAC Traditional name: (5R)-4-hydroxy-3,5-dimethyl-5-(2-methylbuta-1,3-dien-1-yl)thiophen-2-one
• Synonyms: [R-(E)]-4-Hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone; Antibiotic 2-200; (5R)-4-Hydroxy-3,5-dimethyl-5-[(1E)-2-methyl-1,3-butadienyl]-2(5H)-thiophenone

DATABASE IDS

• PubChem SID: 24278631
• CAS Number: 82079-32-1
• MDL Number: MFCD01940028

PROPERTIES

• Empirical Formula (Hill Notation): C11H14O2S
• Purity: 98% (HPLC)
• Gene Information: human ... FASN(2194)
• Apperance: light yellow solid
• Solubility: DMSO: soluble ~21 mg/mL
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: XN1928870
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of bacterial myristate synthesis. Does not inhibit eukaryotic myristate synthesis; antibiotic; antitrypanosomal. Shown to be effective against human sleeping sickness parasite, Trypanosoma brucei, as well as malaria parasite and toxoplasma.

Description (简体中文)

Biochem/physiol Actions
Inhibitor of bacterial myristate synthesis. Does not inhibit eukaryotic myristate synthesis; antibiotic; antitrypanosomal. Shown to be effective against human sleeping sickness parasite, Trypanosoma brucei, as well as malaria parasite and toxoplasma.