Naloxonazine dihydrochloride hydrate

• Catalog No.: N176
• CAS Number: 880759-65-9(anhydrous)
• M. F.: C39H48Cl2N4O7
• M. W.: 755.72702
• Purity: ≥95% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: (1S,5R,13R,17S)-14-{2-[(1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7,9,11(18)-trien-14-ylidene]hydrazin-1-ylidene}-4-(2-methylprop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol hydrate dihydrochloride
• IUPAC Traditional name: (1S,5R,13R,17S)-14-{2-[(1S,5R,13R,17S)-10,17-dihydroxy-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7,9,11(18)-trien-14-ylidene]hydrazin-1-ylidene}-4-(2-methylprop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol hydrate dihydrochloride
• Synonyms: bis[(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone hydrate dihydrochloride

DATABASE IDS

• PubChem SID: 24278602
• CAS Number: 880759-65-9(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C38H42N4O6 · 2HCl · xH2O
• Purity: ≥95% (HPLC)
• Gene Information: human ... OPRM1(4988)
• Apperance: off-white to light tan powder
• Solubility: H2O: >2 mg/mL
• Drug Control: regulated under CDSA - not available from Sigma-Aldrich Canada
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Condition: desiccated
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Potent opioid antagonist that is selective for μ1 opioid receptors.

Description (简体中文)

Biochem/physiol Actions
Potent opioid antagonist that is selective for μ1 opioid receptors.