Imipramine hydrochloride

• Catalog No.: I7379
• CAS Number: 113-52-0
• M. F.: C19H25ClN2
• M. W.: 316.8682
• Purity: ≥99% (TLC)

SYNONYMS

• IUPAC name: (3-{2-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
• IUPAC Traditional name: (3-{2-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
• Synonyms: 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride; 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride

DATABASE IDS

• MDL Number: MFCD00012669
• PubChem SID: 24278097
• CAS Number: 113-52-0
• EC Number: 204-030-7

PROPERTIES

• Empirical Formula (Hill Notation): C19H24N2 · HCl
• Purity: ≥99% (TLC)
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)
• Apperance: white crystalline
• Solubility: H2O: soluble50 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters with Kis of 7.7 nM and 67 nM, respectively. Has little effect on the dopamine transporter (Ki = 25 μM).

Description (简体中文)

Biochem/physiol Actions
Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters with Kis of 7.7 nM and 67 nM, respectively. Has little effect on the dopamine transporter (Ki = 25 μM).