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6-Chloromelatonin_Molecular_structure_CAS_63762-74-3)
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6-Chloromelatonin

Catalog No. C0331 Name Sigma Aldrich
CAS Number 63762-74-3 Website http://www.sigmaaldrich.com
M. F. C13H15ClN2O2 Telephone 1-800-521-8956
M. W. 266.7234 Fax
Purity Email
Storage Chembase ID: 105314

SYNONYMS

Title
6-氯褪黑激素
IUPAC name
N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide
IUPAC Traditional name
N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide
Synonyms
N-乙酰基-6-氯-5-甲氧基色胺
N-Acetyl-6-chloro-5-methoxytryptamine

DATABASE IDS

CAS Number 63762-74-3
MDL Number MFCD00209923

PROPERTIES

Empirical Formula (Hill Notation) C13H15ClN2O2
Gene Information human ... MTNR1A(4543), MTNR1B(4544)
Solubility alcohol: soluble
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H301-H311-H315-H319-H331-H335-H360
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P261-P280-P301 + P310-P305 + P351 + P338-P311
Risk Statements 60-23/24/25-36/37/38
RTECS AB5750000
Safety Statements 53-26-36/37/39-45
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Melatonin agonist active at nanomolar concentrations; binds more strongly than melatonin at the receptor. Also has binding sites outside the CNS, i.e., at the adrenal gland. Possesses antiproliferative activity.
Description (简体中文)
Biochem/physiol Actions
纳摩尔浓度级褪黑激素激动剂活性物质;受体结合能力比褪黑激素更强。在 CNS 外也有结合位点,例如肾上腺的结合位点。具有抗增殖活性。

REFERENCES