Melphalan

• Catalog No.: M2011
• CAS Number: 148-82-3
• M. F.: C13H18Cl2N2O2
• M. W.: 305.20022

SYNONYMS

• IUPAC name: (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid
• IUPAC Traditional name: melphalan
• Synonyms: L-Phenylalanine mustard; L-PAM; 4-[Bis(2-chloroethyl)amino]-L-phenylalanine

DATABASE IDS

• CAS Number: 148-82-3
• Beilstein Number: 2816456
• EC Number: 205-726-3
• MDL Number: MFCD00057717
• PubChem SID: 24278538

PROPERTIES

• Empirical Formula (Hill Notation): C13H18Cl2N2O2
• Apperance: white powder
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H330-H350-H361
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P260-P264-P280-P284-P302 + P350
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 45-46-63-26/27/28
• RTECS: AY3675000
• Safety Statements: 53-22-36/37/39-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Melphalan is an antineoplastic agent.1,2 It forms DNA intrastrand crosslinks by bifunctional alkylation in 5′-GGC sequences.3

Description (简体中文)

Biochem/physiol Actions
Melphalan is an antineoplastic agent.1,2 It forms DNA intrastrand crosslinks by bifunctional alkylation in 5′-GGC sequences.3